Just Installed:
Waters Select Series Cyclic Ion Mobility Quadruple Time of Flight Mass Spectrometer:
High Resolution Mass and Ion Mobility Resolution performance
− Mass up to 100K (FWHM)
− IMS up to 500 (FWHM)
− 500 ppb Mass Accuracy (RMS)
− 4-orders LDR
Excellent performance for routine Q-IMS-ToF screening
Instrument geometry provides unique experimental flexibility
− Multiple fragmentation options
− HDMSe/SONAR DIA
− Novel multi-stage IMSn capability
− Research scripting control available
Dual UPLC and GC Coupling Capabilities
− Waters Acuity I and H class UPLCs
− Agilent 8890 GC
Recently Added:
Agilent 8900 ICP MS (New installation May 2023)
HPLC: Agilent 1260 Bioinert system
Applications: Metal Analysis, Elemental Speciation.
*The instrument was supported by the NIH S10 award (S10OD032210) and North Carolina Biotechnology Center Innovation Impact Grant (2022-IIG-6507).
Representative Publication:
Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease. Cell Host Microbe. 2025 Jan 8;33(1):71-88.e9. doi: 10.1016/j.chom.2024.11.012. Epub 2024 Dec 18. PubMed PMID: 39701098.
Agilent 5977C MSD / 8860 GC (New installation May 2023)
Applications: Volatile Compounds.
Continuously Running
Agilent 6520 Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) MS
HPLC: Agilent 1200 HPLC system
Applications: small molecules, proteins, nuclear acids, etc
AB Sciex QTRAP 6500 MS
LC: Agilent 1290 Infinity II UPLC System or Eksigent nanoLC
Applications: Quantitation of small molecules in diverse sample matrices
Mass Spec:
Thermo TSQ Quantum Ultra Triple Quadrupole MS
LC: Waters Acquity UPLC
Applications: Quantitation of small molecules in diverse sample matrices
Thermo TSQ Quantum Ultra Triple Quadrupole MS
HPLC: Thermo Accela HPLC system
Applications: Quantitation of small molecules in diverse sample matrices
